Search results for "Scanning laser ophthalmoscopy"

showing 7 items of 7 documents

Confocal scanning laser ophthalmoscopy versus modified conventional fundus camera for fundus autofluorescence.

2016

Fundus autofluorescence (FAF) is a noninvasive imaging method to detect fundus endogenous fluorophores, mainly lipofuscin located in the retinal pigment epithelium (RPE). The FAF provides information about lipofuscin distribution and RPE health, and consequently an increased accumulation of lipofuscin has been correlated with ageing and development of certain retinal conditions. Areas covered: An exhaustive literature search in MEDLINE (via OVID) and PUBMED for articles related to ocular FAF in retinal diseases and different devices used for acquiring FAF imaging was conducted. Expert commentary: This review aims to show an overview about autofluorescence in the RPE and the main devices use…

0301 basic medicinemedicine.medical_specialtygenetic structuresFundus OculiBiomedical EngineeringFundus (eye)Fundus cameraFluorescenceLipofuscin03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOpticsOphthalmologymedicinePhotographyHumansFluorescent DyesRetinal pigment epitheliumbusiness.industryLasersRetinalGeneral Medicineeye diseasesFundus autofluorescenceConfocal scanning laser ophthalmoscopyOphthalmoscopyAutofluorescence030104 developmental biologymedicine.anatomical_structurechemistry030221 ophthalmology & optometrySurgerysense organsbusinessExpert review of medical devices
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Structure-function relationship between FDF, FDT, SAP, and scanning laser ophthalmoscopy in glaucoma patients.

2012

Purpose Flicker defined form perimetry (FDF) and frequency doubling technology perimetry (FDT) are alleged to detect glaucoma at an earlier stage than standard automated perimetry (SAP). It is the purpose of this study to investigate the structure-function relationship between FDF, FDT, SAP, and confocal scanning laser ophthalmoscopy (cSLO) in patients with glaucoma. Methods Seventy-six patients with glaucoma were included in the study. Patients were tested with SAP, Matrix-FDT, FDF perimetry, and cSLO. Structure-function relationships between global and sectoral cSLO parameters and global and sectoral mean sensitivity (MS) of SAP, Matrix-FDT, and FDF were calculated using Spearman's rank c…

AdultMaleRetinal Ganglion CellsIntraocular pressuremedicine.medical_specialtygenetic structuresGlaucomaOphthalmologyLinear regressionmedicineHumansIn patientTomographyIntraocular PressureMathematicsRank correlationRetrospective StudiesAutomated perimetryStructure functionReproducibility of ResultsGlaucomaMiddle Agedmedicine.diseaseeye diseasesScanning laser ophthalmoscopyOphthalmoscopyVisual Field TestsFemaleVisual FieldsInvestigative ophthalmologyvisual science
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Flicker Defined Form Perimetry in Glaucoma Suspects with Normal Achromatic Visual Fields

2014

To evaluate if repeated flicker-defined form (FDF) perimetry can detect visual field (VF) defects in glaucoma suspects with normal findings in achromatic standard automated perimetry (SAP).Patients with optic nerve heads (ONHs) or retinal nerve fiber layer (RNFL) findings clinically suspicious for glaucoma and normal SAP were enrolled. Patients underwent VF testing with FDF perimetry (Heidelberg Edge Perimetry, HEP) at two consecutive visits (HEP I and HEP II) and confocal scanning laser ophthalmoscopy with the Heidelberg Retina Tomograph (HRT). Abnormal HEP was defined by cluster-point analysis (CPA) and by the HEP specific glaucoma hemi-field test (GHT). Results were compared with an age-…

AdultMaleRetinal Ganglion Cellsmedicine.medical_specialtygenetic structuresOptic DiskVision DisordersVisual AcuityNerve fiber layerGlaucomalaw.inventionTonometry OcularCellular and Molecular Neurosciencechemistry.chemical_compoundNerve FiberslawOphthalmologymedicineHumansProspective StudiesIntraocular PressureHeidelberg retina tomographOptic Nerve Headsbusiness.industryGlaucomaRetinalMiddle Agedmedicine.diseaseeye diseasesSensory SystemsVisual fieldConfocal scanning laser ophthalmoscopyOphthalmologyEarly Diagnosismedicine.anatomical_structurechemistryAchromatic lensVisual Field TestsFemaleOcular Hypertensionsense organsVisual FieldsbusinessCurrent Eye Research
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Blood vessel segmentation and width estimation in ultra-wide field scanning laser ophthalmoscopy.

2014

Features of the retinal vasculature, such as vessel widths, are considered biomarkers for systemic disease. The aim of this work is to present a supervised approach to vessel segmentation in ultra-wide field of view scanning laser ophthalmoscope (UWFoV SLO) images and to evaluate its performance in terms of segmentation and vessel width estimation accuracy. The results of the proposed method are compared with ground truth measurements from human observers and with existing state-of-the-art techniques developed for fundus camera images that we optimized for UWFoV SLO images. Our algorithm is based on multi-scale matched filters, a neural network classifier and hysteresis thresholding. After …

Ground truthArtificial neural networkLaser scanningComputer sciencebusiness.industryMatched filterComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONField of viewAtomic and Molecular Physics and OpticsArticleScanning laser ophthalmoscopySpline (mathematics)SegmentationComputer visionArtificial intelligencebusinessBiotechnologyBiomedical optics express
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The Heidelberg retina tomograph ancillary study to the European glaucoma prevention study: study design and baseline factors.

2013

Purpose: To describe the study design and baseline factors of the Heidelberg Retina Tomograph ancillary study within the EGPS. Furthermore, to examine the relationship between HRT optic disc topographic measurements and baseline demographic and ocular factors. Methods: Four hundred and eighty-nine ocular hypertensive participants were included. Each participant completed HRT imaging at least annually. The associations between HRT measurements and IOP, central corneal thickness (CCT), baseline photographic estimates of vertical CDR ratio (CDR), asymmetry between the two eyes in CDR ratio and baseline visual field indices were assessed using regression analysis. Results: Associations between …

MaleIntraocular pressureVisual acuitygenetic structuresOptic diskVisual AcuityOcular hypertensionGlaucomaOptic Nerve DiseasesMedicineHRT parameterCarbonic Anhydrase Inhibitorspattern standard deviationTomographySulfonamidesmedicine.diagnostic_testGeneral MedicineMiddle Agedmedicine.anatomical_structureResearch DesignOptic nerveFemalemedicine.symptomHumanOptic discmedicine.medical_specialtyCarbonic Anhydrase Inhibitorscanning laser ophthalmoscopyOptic DiskVisual FieldThiophenesSulfonamideOphthalmoscopyTonometry OcularOptic Nerve DiseaseDouble-Blind MethodThiopheneOphthalmologymental disordersHumansIntraocular Pressurebusiness.industryGlaucomamedicine.diseaseeye diseasesOphthalmoscopyOphthalmologyOcular Hypertensionsense organsVisual Fieldsbusinesscentral corneal thickneActa ophthalmologica
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A/V ratio as predicted by full width at half maximum and by blood vessel tracking in presence of ocular aberrations

2011

Aberrations impact A/V ratio calculated from full width at half maximum. We investigated whether aberrations affect A/V ratio calculated by tracking the vessels. Aberrations changed the A/V ratio. We conclude that aberrations impact A/V ratio.

PhysicsFull width at half maximummedicine.anatomical_structureOpticsIntraocular lensesbusiness.industrymedicineTracking (particle physics)businessAdaptive opticsBlood vesselScanning laser ophthalmoscopy
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Retinal vasculature segmentation and measurement framework for color fundus and SLO images

2020

Abstract The change in vascular geometry is an indicator of various health issues linked with vision and cardiovascular risk factors. Early detection and diagnosis of these changes can help patients to select an appropriate treatment option when the disease is in its primary phase. Automatic segmentation and quantification of these vessels would decrease the cost and eliminate inconsistency related to manual grading. However, automatic detection of the vessels is challenging in the presence of retinal pathologies and non-uniform illumination, two common occurrences in clinical settings. This paper presents a novel framework to address the issue of retinal blood vessel detection and width me…

business.industryComputer scienceBiomedical EngineeringRetinalVascular geometryFundus (eye)Scanning laser ophthalmoscopychemistry.chemical_compoundchemistryIterative thresholdingAutomatic segmentationGraph (abstract data type)SegmentationComputer visionArtificial intelligencebusinessBiocybernetics and Biomedical Engineering
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